Got up and installed the new patches via the tweaker and now I'm getting to the Sega logo before it up and crashes. I've seen a few other similar a posts in the last few days with little to no response, thus I'm not expecting a huge fix thrown at me. Just a bummer!
If anyone has any advice, that would be great. Will probably do a clean reinstall one more time and if I can't get any luck from that, I'll just have to move on to another game.
EDIT: the crash is also causing my "OneDrive" to restart every time.
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