Right as PSO started, actually. The explosion that shook the planet was his doing (unsealed Falz) and that's when he became infected and was shipped off to Gal Da Val.
Of course, PSO Episode 2 is quite a bit after that.
EDIT: Might be wrong actually, but I don't think it's *that* long before _(:3」∠)_ However in PSP2I you actually manage to free Flowen or something instead of him being damaged beyond repair (as in PSO E2)
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