Raw reflex doesn't matter in the game outside of a selected few situations, like instant Masquerade moves, which you can predict and pre-emptively dodge because he has to combo them from something. Rest of everything has tells well beyond 0.5 second long, even if you account for not being immediately able to recognize the attack animation. Bottom of human reflexes without actual impairment is somewhere around 0.4 or so raw. The real problem is choice reaction. Humans get confused and react much slower when they are presented with something like having to press the button whose colour appears on screen on similar. Complicated responses are much slower than basic reaction to stimuli, be it visual, audio or touch. Complicated response time can be more effectively shortened by training though.
90% of action games isn't really about having above average reflexes, but merely drilling the proper responses so you stop thinking of what action to perform and start reacting. Sekiro was the game where I tested it myself the most. First run I was getting absolutely destroyed by perilous attacks which you had to dodge with the proper response unlike normal ones, but on NG+ nearly all perilous attacks became counter fodder for me, all because I stopped looking at the sign and thinking whether I should jump or dodge forward or dodge to the side. I just knew what it will be.
You can even add onto it other stuff like experience with boss patterns letting you see more than merely connecting tell with attack animation, but rather pay attention to attacks that are on cooldown after use, some more sophisticated ways bosses combo their attacks, Deus alternating between swiping hand and punching in his torso phase with other attacks between. A lot of things that aren't related to raw horsepower of your neutral pathways help you react to fast attack or slow you down when trying to react to something that's actually pretty slow. You shouldn't really pay that much attention to reaction time below 40 years old.
It's all pretty offtopic but eh, I like talking about reaction times and their effect on performance and similar.
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