How has nobody mentioned Saner yet? It increases your agility, making sure you pretty much always act before the enemy, and it makes you hard to hit. Couple it with Wren's Barrier and Deban/Warla/Blessing, and you're pretty much set for defences.
Have a buff Macro set up for the final boss, by the way. It dispels buffs fairly frequently and usually follows up with lots and lots of damage.
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