The idea is to have ability III stat III and soul so instead of +60 total you get +75.
An extra 15 is an extra 15. Not worth it imo, but if you're a min-maxer like some people that extra ~1% damage is a big deal.
and yes, any affix that fails means you lose a slot so if 1 fails your 3 slot becomes a 2, if two fail your 3 slot becomes a 1 and if all 3 fail you go back to 0. so you want to minimize this risk as best you can.
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