I had something similar - within anywhere between ten seconds and about two minutes of starting the game, it'd just... freeze. There'd be that blue loading-circle cursor thingy, I could move the actual mouse cursor around, but the game simply wouldn't respong and clicking anythwere on the screen popped up an error message about program not reponding, terminate?
Eventually turned out the problem was Raptr. Turning that off fixed the problem.
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